Top 10 Best Substance Abuse

10. Candy, 2006
Candy is a 2006 Australian romantic drama film, adapted from Luke Davies's novel Candy: A Novel of Love and Addiction. Candy was directed by debut film-maker Neil Armfield and stars Heath Ledger, Abbie Cornish and Geoffrey Rush.
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9. Traffic, 2000
Traffic is a 2000 American crime drama film directed by Steven Soderbergh and written by Stephen Gaghan. It explores the illegal drug trade from a number of perspectives: a user, an enforcer, a politician and a trafficker.
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8. Shrink, 2009
Shrink is a 2009 American independent film about a psychologist who treats members of the entertainment industry in Los Angeles, California. It stars an ensemble cast headed by Kevin Spacey as Dr. Henry Carter.

7. Trainspotting, 1996
Mark Renton (Ewan McGregor), a young man with few prospects and fewer ambitions, lives in economically depressed Edinburgh. Like most of his friends, Renton is a heroin addict who loves the drug's blissful nothingness; financing his habit also provides excitement and challenges that his life otherwise lacks. Renton's two best friends are also junkies: Sick Boy (Jonny Lee Miller), a snappy dresser obsessed with James Bond, and Spud (Ewan Bremner), a guileless nerd who suggests Pee Wee Herman's debauched cousin.

6. Drugstore Cowboy, 1989
The operative word in Drugstore Cowboy is drug. Matt Dillon plays the leader of a group of dopeheads who wander around the country robbing pharmacies to feed their habits. Dillon's chums include doltish James Le Gros and teen-age junkie Heather Graham; also along for the ride is Dillon's wife Kelly Lynch. Their nemesis is cop James Remar, whom Dillon takes perverse delight in humiliating. When one of the young addicts dies of an overdose, it promps Dillon to try to go straight, a task complicated by wife Lynch's determination to stay high and by the corrupting presence of an ex-priest, played by Naked Lunch author William Burroughs. Drugstore Cowboy was director Gus Van Sant's breakthrough picture.
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5. Leaving Las Vegas, 1995
Leaving Las Vegas is a 1995 romantic drama film written and directed by Mike Figgis and based on a semi-autobiographical novel of the same name by John O'Brien.
Image Source: http://www.film4.com/media/images/Channel4/Film4/1990s/L/leaving-las-vegas.jpg

4. Spun, 2003
Spun is a 2002 American crime dark comedy-drama directed by Jonas Åkerlund from an original screenplay by William De Los Santos and Creighton Vero, based on 3 days of De Los Santos' life in the Eugene, Oregon drug subculture and stars Jason Schwartzman, John Leguizamo, Mena Suvari, Patrick Fugit, Peter Stormare, Alexis Arquette, Deborah Harry, Eric Roberts, Chloe Hunter, Nicholas Gonzalez, Brittany Murphy and Mickey Rourke.

3. Pink Floyd – The Wall, 1982
Pink Floyd's 1979 album The Wall is one of the most creative productions in the history of rock music, choreographed to stunning digital imagery under the planetarium's 360-degree multimedia dome.

2. Requiem for a Dream, 2000
Requiem for a Dream is a 2000 American psychological drama film directed by Darren Aronofsky and starring Ellen Burstyn, Jared Leto, Jennifer Connelly, and Marlon Wayans.
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1. Fear and Loathing in Las Vegas, 1998
Fear and Loathing in Las Vegas is a 1998 American dark comedy film co-written and directed by Terry Gilliam, starring Johnny Depp as Raoul Duke and Benicio del Toro as Dr. Gonzo. It was adapted from Hunter S. Thompson's 1971 novel of the same name.
Image Source: http://www.arts-wallpapers.com/movie_wallpapers/fear_and_loathing_in_las_vegas/img12.jpg